PRF (Platelet Rich Fibrin)

How Does PRF Work?

Fibrin is a biological scaffold that forms in response to an injury anywhere in the body. Platelets circulating in the blood will bind to a scaffold of fibrin. When platelets bind to the fibrin scaffold, they become activated and release growth factors, which start the wound healing process by creating new skin cells, collagen and blood vessels. By injecting PRF into an area on the face or scalp, a controlled inflammatory response is created, which kick starts new cell growth and collagen production.

How Is PRF Used?

PRF (second-generation PRP) is used to address poor skin texture and tone, acne, scarring, and assist in rejuvenating the skin. PRF releases growth factors up to one week versus PRP which releases growth factors for only few hours. This means that PRF could have better longer-term benefits. The growth factors are what stimulate the stem cells to improve collagen and elastin in the skin. The platelets in PRF are thought to be more robust than those in PRP, and to therefore promote faster healing.

The prepared PRF is immediately ready for injection into the face to fill facial folds and wrinkles, to plump the hollows under the eyes, and to improve skin tone and texture through RF Microneedling. The PRF can also be injected into the scalp to aid with hair restoration and growth or utilized in conjunction.

The prepared PRF is utilized immediately

  • as an add-on to RF Microneedling (collagen induction therapy) to rejuvenate the skin by improving tone and texture.
  • as in injection similar to dermal fillers and neurotoxins.
  • as an injection into the scalp to aid with hair restoration and growth.

The number of treatments will depend on our desired outcome, age, at-home skin care routine, etc. Your provider will discuss these topics and expectations at the consult.

What is the difference between PRP and PRF?

Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) are both platelet concentrates prepared by drawing and centrifuging your own blood. This in turn becomes the body’s own healing serum!

The natural healing properties found in both PRP and PRF make them superior compared to man-made or synthetic products for use in cosmetic  treatments such as microneedling or injections. By drawing a patient’s blood and using their own plasma for these treatments, we are utilizing the purest and most natural form of growth factors possible, giving exceptional results when treating acne, scarring, skin tone and texture, and rejuvenating the skin.

Platelet Rich Plasma is the derivative of blood centrifuged at a high speed. The blood is separated into two different layers, leaving the heavier red, white, and stem cells at the bottom while the lighter weight platelets and plasma are able to be collected from the top of a tube.

Platelet Rich Fibrin is a second-generation PRP. It is still derived from your own blood, but centrifuged at a lower speed separating the blood into layers that are not as distinct as with PRP.  This results in white blood cells (leukocytes), stem cells, and growth factors in addition to the platelets to be collected from a tube that has no anticoagulant additive.  It is these additional elements that make PRF a much more desired product when used in skin care treatments.

What can I Expect?

PRF treatments provide longer-lasting results as they continue to release growth factors over time. A series of treatments will provide the best results. Results may vary from patient to patient due to several factors like age, skin issues, and at-home routine.

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